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The first opioid drug, synthesized from opium, morphine comes in several brand names and is still prescribed to treat pain in the United States and much of the world. However, concerns about the addictive nature of morphine, especially after the Civil War, led to the development or heroin and other opioid analgesics, which have also proven to have serious addiction potential. All opioids, whether illicit or prescription, are based on morphine.
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